Studies using radiolabelled aerosols in children.

نویسنده

  • M L Everard
چکیده

Although more than 20 years have passed since radioisotopes were first used to study the deposition of aerosols in the respiratory tract of children,' such studies have only recently become relatively more common.2 The reason for this lies in the widespread concern regarding the use of radioisotopes for research purposes in childhood. Indeed, this concern is such that certain journals have rejected studies, not on the basis of their scientific content, but upon the editor's view that such studies are essentially unethical. However, information obtained from such studies is becoming increasingly important as the number of expensive and potent therapeutic agents being delivered by this route increases.7 The purpose of this paper is to review radiation protection and ethical issues relating to the use of radioisotopes in research projects involving children. It then goes on to discuss technical aspects relevant to those interested in designing or interpreting radiolabelled aerosol deposition studies in children.

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عنوان ژورنال:
  • Thorax

دوره 49 12  شماره 

صفحات  -

تاریخ انتشار 1994